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Health and Science

What you need to know about the Zika virus

The virus that is sweeping across the Americas is not new, but it has commanded attention as scientists have begun to connect it to steep rises in a serious birth defect and a rare autoimmune disorder. Latest news: WHO issues travel warning for pregnant women

How a bloodsucker transmits the Zika virus

The Aedes aegypti mosquito is the perfect vector for spreading the virus. It picks up the virus from a human, then can infect another person as it injects saliva from its tiny syringe-like proboscis.

Mosquitoes are measured by wing length. The yellow fever mosquito, Aedes aegypti, has wings that are, at most, 1/8 inch long.

Capillaries

Seeking a blood meal

As she probes for a blood vessel, a female mosquito saws her proboscis back and forth under the skin. She injects saliva, which acts as an anesthetic and prevents blood from clotting once she strikes a capillary.

Midgut

Infecting the vector

After piercing a vessel, the mosquito pumps blood into her midgut. Should her host be infected with Zika, the blood will contain tiny virus particles, each less than 1/100th the diameter of a red blood cell.

Zika virus

particle

Diameter:

50 nanometers

Edge of red blood cell

7,000 nanometers

Hemolymph

Heart

Salivary

glands

Passing it on

Viruses migrate out of the gut and into the insect’s body cavity, which is filled with hemolymph, or insect blood, which is pumped throughout the body cavity by a long, tubular heart. Viruses ultimately penetrate the saliva glands, where they are poised to be injected into another person.

Mosquitoes are measured by wing length. The yellow fever mosquito, Aedes aegypti, has wings that are, at most, 1/8 inch long.

Seeking a blood meal

As she probes for a blood vessel, a female mosquito saws her proboscis back and forth under the skin. She injects saliva, which acts as an anesthetic and prevents blood from clotting once she strikes a capillary.

Capillaries

Infecting the vector

Midgut

After piercing a vessel, the mosquito pumps blood into her midgut. Should her host be infected with Zika, the blood will contain tiny virus particles, each less than 1/100th the diameter of a red blood cell.

Zika virus particle

Diameter:

50 nanometers

Edge of red blood cell

7,000 nanometers

Hemolymph

Passing it on

Heart

Viruses migrate out of the gut and into the insect’s body cavity, which is filled with hemolymph, or insect blood, which is pumped throughout the body cavity by a long, tubular heart. Viruses ultimately penetrate the saliva glands, where they are poised to be injected into another person.

Salivary

glands

Zika virus particle

Diameter: 50 nanometers

Mosquitoes are measured by wing length. The yellow fever mosquito, Aedes aegypti, has wings that are, at most, 1/8 inch long.

Edge of red blood cell

7,000 nanometers

Midgut

Hemolymph

Heart

Salivary

glands

Capillaries

Passing it on

Seeking a blood meal

Infecting the vector

As she probes for a blood vessel, a female mosquito saws her proboscis back and forth under the skin. She injects saliva, which acts as an anesthetic and prevents blood from clotting once she strikes a capillary.

After piercing a vessel, the mosquito pumps blood into her midgut. Should her host be infected with Zika, the blood will contain tiny virus particles, each less than 1/100th the diameter of a red blood cell.

Viruses migrate out of the gut and into the insect’s body cavity, which is filled with hemolymph, or insect blood, which is pumped throughout the body cavity by a long, tubular heart. Viruses ultimately penetrate the saliva glands, where they are poised to be injected into another person.

The differences between mosquitoes

Scientists say Aedes aegypti is the main transmitter of the Zika virus, but other types of mosquitoes may be contributing as well. The similar-looking Aedes albopictus, which thrives in more temperate climates, is a prime suspect. One challenge with eradicating these mosquitoes is that their eggs can withstand months without water, then can hatch when water returns.

Aedes aegypti

Primary carrier of Zika

Aedes albopictus

Suspected secondary carrier

Common name

Yellow fever mosquito

Common name

Asian tiger mosquito

Identifying traits

Dark and small (4-7mm long) with white-banded legs and a silvery lyre-shaped pattern on its thorax

Identifying traits

Also dark and similar in size (2-10mm) with white-banded legs and a silvery lengthwise stripe down its thorax

Region

Prefers to live among humans, especially in urban areas, in the tropics and subtropics

Region

Can live in temperate regions but prefers areas with thick vegetation

Habitat

Lives indoors and outdoors, preferably in shade

Habitat

Lives and bites mostly outdoors

Breeding

Prefers to lays eggs in manmade containers of standing water such as empty pots, buckets and pet dishes

Breeding

Likes to lay eggs in standing water in treeholes but will also lay them in old tires and other manmade containers as well

Biting habits

Bites humans, sometimes multiple times, usually in daytime

Biting habits

Feeds in daytime but targets animals as well as people, so it is less effective at transmitting viruses between people

Lifespan

2–4 weeks

during which a female can produce up to five batches of eggs

Lifespan

30-40 days

during which a female can produce up to four batches of eggs

Travel habits

Weak flier; rarely travels more than 150 feet from where it hatches

Travel habits

Also a weak flier and may never leave its original habitat

Origin

Africa. Likely came to Americas on ships

Origin

Eastern Asia and several Pacific Islands

Examples of viruses it carries

Dengue, chikungunya, yellow fever

Examples of viruses it carries

Dengue, Eastern equine encephalitis

Serious conditions linked to Zika

For most people, a Zika infection is not a big deal. Only 1 in 5 will get sick, and those who do tend to have a few days of fever, rash and other mild symptoms. The problem is that areas affected by the Zika outbreak are seeing an unusual rise in some serious conditions, and evidence points to the virus as the cause.

Zika

First identified in humans in 1952, it is very similar to viruses that cause dengue, West Nile and yellow fever.

COULD AFFECT:

Pregnant women or women

trying to become pregnant

Microcephaly

Microcephaly means a baby’s head is smaller than expected and usually

indicates that the brain didn’t develop properly. Many different things can cause microcephaly. Health officials say the Zika link is strong, and the virus appears to cause the most harm early in the pregnancy.

Other birth defects

Other birth defects may be associated with the Zika virus as well, including some that led to stillbirth or death

shortly after birth. Miscarriages have been reported in women who have had Zika, but it is not known if the virus

contributed to the miscarriages.

COULD AFFECT:

Anyone

Guillain-Barré syndrome

The body’s immune system attacks

protective sheaths around nerve cells, causing weakness and paralysis. An uptick in cases occurs after some

outbreaks of viral illnesses, including flu. It is fatal about 5 percent of the time, according to the WHO.

Zika

First identified in humans in 1952, it is very similar to viruses that cause dengue, West Nile and yellow fever.

COULD AFFECT:

COULD AFFECT:

Pregnant women or women

trying to become pregnant

Anyone

Microcephaly

Guillain-Barré syndrome

The body’s immune system attacks protective sheaths around nerve cells, causing weakness and paralysis. An uptick in cases occurs after some outbreaks of viral illnesses, including flu. It can be fatal. It is fatal about 5 percent of the time, according to the WHO.

Microcephaly means a baby’s head is smaller than expected and usually indicates that the brain didn’t develop properly. Many different things can cause microcephaly. Health officials say the Zika link is strong, and the virus appears to cause the most harm early in the pregnancy.

Other birth defects

Other birth defects may be associated with the Zika virus as well, including some that led to stillbirth or death shortly after birth. Miscarriages have been reported in women who have had Zika, but it is not known if the virus contributed to the miscarriages.

Zika

First identified in humans in 1952, it is very similar to viruses that cause dengue, West Nile and yellow fever.

COULD AFFECT:

COULD AFFECT:

Pregnant women or women trying to become pregnant

Anyone

Other birth defects

Microcephaly

Guillain-Barré syndrome

The body’s immune system attacks protective sheaths around nerve cells, causing

weakness and paralysis. An uptick in cases occurs after some outbreaks of viral illnesses, including flu. It is fatal about 5 percent of the time, according to the WHO.

Other birth defects may be associated with the Zika virus as well, including some that led to stillbirth or death shortly after birth. Miscarriages have been reported in women who have had Zika, but it is not known if the virus contributed to the miscarriages.

Microcephaly means a baby’s head is

smaller than expected and usually indicates that the brain didn’t develop properly. Many different things can cause microcephaly. Health officials say the Zika link is strong, and the virus appears to cause the most harm early in the pregnancy.

How do you get Zika?

The virus can be transmitted through sex, but it is usually carried person-to-person through Aedes aegypti mosquitoes. In a few cases, mothers have passed Zika to newborns. Read more.

The predicted distribution of Aedes aegypti mosquitoes based on a statistical model.

Probability of occurrence

Low

High

Jan.

isotherm

10°C

July

isotherm

10°C

The contour lines of the January and July isotherms indicate the potential geographic limits of the Northern and Southern hemispheres for year-round survival of A. aegypti.

Probability of occurrence

Low

High

10°C

January

isotherm

July

isotherm

10°C

The contour lines of the January and July isotherms indicate the potential geographic limits of the Northern and Southern hemispheres for year-round survival of A. aegypti.

10°C

January

isotherm

Probability of occurrence

Low

High

July

isotherm

The contour lines of the January and July isotherms indicate the potential geographic limits of the Northern and Southern hemispheres for year-round survival of A. aegypti.

10°C

Researchers writing in the Lancet calculated that about 200 million people in the United States live in areas where Zika could spread in warm months and that another 22.7 million live in subtropical areas where it could spread year-round.

Where is it?

The current outbreak began in May 2015 in Brazil, and the virus is being transmitted locally by mosquitoes in more than three dozen other countries and territories. The continental United States is not included in that number because confirmed U.S. cases occurred after travelers were bitten abroad. The CDC recommends that pregnant women avoid traveling to these countries unless they will be at elevations above about 6,500 feet, which is higher than Zika-carrying mosquitoes generally live.

Active Zika Virus Transmission

What does it feel like?

A Zika infection is diagnosed by a blood test and has some of the same symptoms as early dengue fever, though only 20 percent of those infected will have any symptoms at all. Symptoms typically last two to seven days.

Common symptoms:

  • Fever
  • Rash
  • Joint pain
  • Conjuctivitis (pinkeye)

Rarer symptoms:

  • Muscle pain
  • Headache

How do you treat it?

There is no Zika-specific medication, but you can treat the symptoms:

  • Rest
  • Drink plenty of fluids to prevent dehydration
  • Take a pain reliever/fever reducer such as acetaminophen, but do not take aspirin or nonsteroidal anti-inflammatories (NSAIDS) such as ibuprofen or naproxen until dengue is ruled out.
  • Once you recover from a Zika infection, you are immune, at least for a while. But scientists don’t know how long that immunity lasts.

How do you prevent it?

Any vaccine is still months — or even years — away, so the key is not to get bitten in the first place. If you’re in mosquito country, use insect repellent outdoors and wear protective clothing with long sleeves and long pants, especially during daytime when these mosquitoes are out and eager to bite.

Contraceptive prevalence in countries with Zika

Many countries in Latin America and the Caribbean where Zika has been locally transmitted have restrictive abortion policies, and contraceptives in these areas are often hard to obtain.

Least restrictive: Abortion is legal

World avg.

64

Guyana

44.8%

Mexico

72.6

40

60

80%

Contraceptive

prevalence rate

Some restrictions: Abortion only

legal for certain reasons or to

save a woman’s life

Colombia

78.2

Bolivia

62.5

Barbados

60.3

Panama

61.3

Restrictive: Abortion only legal to

save a woman’s life and/or to

preserve her health

Costa Rica

78.9

Brazil

79

Ecuador

72.6

Highly restrictive: Abortion legal

only to save a woman’s life

Haiti

37.8

Suriname

51.8

Venezuela

70

Honduras

72.7

Guatemala

57.2

Paraguay

77.4

Most restrictive: Abortion is illegal

El Salvador

70.7

D.R.

71.8

Nicaragua

79.5

Least restrictive: Abortion is legal

World avg.

64

Guyana

44.8%

Mexico

72.6

40

60

80%

Contraceptive

prevalence rate

Some restrictions: Abortion only

legal for certain reasons or

to save a woman’s life

Barbados

60.3

Colombia

78.2

Bolivia

62.5

Panama

61.3

Restrictive: Abortion only legal

to save a woman’s life and/or

to preserve her health

Ecuador

72.6

Costa Rica

78.9

Brazil

79

Highly restrictive: Abortion legal only to save a woman’s life

Haiti

37.8

Suriname

51.8

Venezuela

70

Guatemala

57.2

Honduras

72.7

Paraguay

77.4

Most restrictive: Abortion is illegal

El Salvador

70.7

Dom. Rep.

71.8

Nicaragua

79.5

Note: Contraceptive prevalence rates are of any method, and data is as of 2015. Abortion policies are as of 2013.